药物
美国和英格兰处方量最大的药物，以及它们在你体内改变了什么。
英文页面
Statins
Statin harms to muscle, kidney, liver, glucose control and brain vessels, the isoprenoid branches and tissues they reach, and absolute benefit against harm.
Omeprazole and other proton-pump inhibitors
Kidney injury, low magnesium, infection, fracture, B12 and skin harms of PPIs, and their effects on gastrin, gut bacteria, minerals and drug activation.
Levothyroxine
Levothyroxine harms to heart rhythm, vessels, bone, brain, adrenal glands and child growth, its actions on liver, muscle and glucose, and its measured benefit.
Metformin
Metformin's lactic acidosis, B12, hypoglycaemia, liver and offspring harms, and the transporters and mitochondrial targets it reaches.
Amlodipine
Amlodipine harms to heart, kidneys, liver, skin and lungs, its calcium-channel target in brain, gut, bladder and pancreas, and its absolute benefit.
ACE inhibitors and angiotensin receptor blockers
Angio-oedema, hyperkalaemia, kidney, fetal, blood and cancer harms of ACE inhibitors and receptor blockers; bradykinin, renin, urate and glucose effects.
Beta-blockers
Beta-blocker harms to heart, airways, glucose, newborns and mood, at surgery and withdrawal; lipid, thyroid, urate and sleep effects; benefit against harm.
Salbutamol
Salbutamol harms to airways, blood acid, potassium, heart rhythm, pregnancy and with overuse; its reach into heart, muscle, glucose, fat and brain.
Sertraline
Suicidality under 25, serotonin syndrome, bleeding, low sodium, falls, newborn harms and withdrawal; serotonin in gut, platelets, bone, immune cells and pineal.
Folic acid
Folic acid harms from masked B12 nerve damage, anaphylaxis, seizures, restenosis, kidney decline and cancer signals; methylation, transport and tumour effects.
Semaglutide (Ozempic, Wegovy)
Semaglutide harms to pancreas, gallbladder, bowel, kidney, eye, bone and thyroid; effects on stomach, brain, heart and muscle; benefit against harm.